4 Types of Drugs that Induces Peptic Ulcer

In this article, you will discover 4 Types of Drugs that Induces Peptic Ulcers. There has been a drastic increment in the number of ulcerative patients all over the world. Are you aware that aside H. Pylori, certain drugs also cause a peptic ulcer? Keep reading this article for more information.

4 Types of Drugs that Induces Peptic Ulcer

4 Types of Drugs that Induces Peptic Ulcer

A peptic ulcer is a sore that develops on the lining of your stomach and inflicts stomach pains and indigestion. The peptic ulcer is divided into Gastric and Duodenal Ulcers. This is most commonly caused by a bacteria called Helicobacter pylori.

This bacteria infects the stomach, damages its tissue, and causes inflammation. This can result in a burning sensation felt in the stomach, bloating, stomach pain, nausea, etc.

Although, certain drugs have been indicated to cause peptic ulcers. These drugs include:


Drugs that fall under this classification are said to cause ulcers in humans. These are Non-Steroidal Anti-inflammatory Drugs that are widely used to relieve pain, treat inflammation, and lower body temperature. They include:

  • Ibuprofen
  • Aspirin
  • Indomethacin
  • Celecoxib
  • Diclofenac, etc.

Hence, they should be taken under their right prescription, not regular.


Although this has proven controversial for over some time now as other scientists have also warned against its oral consumption unless on prescription. Corticosteroids are medications that provide relief from inflamed areas and lessen swelling, itching and allergic reactions, asthma, bowel diseases, etc.

They include Hydrocortisone, cortisone, and prednisolone. A series of experiments have been conducted with the use of prednisolone to confirm its ability to induce peptic ulcers. Once prostaglandin is inhibited, gastric acid secretion becomes unregulated which could eventually lead to peptic ulcer.

Alendronic Acid

It is a classification of medicine that is used to treat osteoporosis and Paget’s disease of the bone. Its function is to increase the amount of calcium in the human bone, reducing its risk of breaking easily and strengthening it. There are common side effects when taking it. They include;

  • Stomach acid reflux
  • Indigestion
  • Bloating
  • Constipation
  • Stomach pain, etc.

If you notice the above symptoms while taking alendronic acid, consult a pharmacist or a medical doctor and quit the intake of it as this could be a sign of an ulcer in your food pipe, etc.


It falls under the classification known as antiplatelet drugs. These are drugs that prevent platelets from collecting and forming clots that may lead to heart attack or stroke. These drugs are not sold over-the-counter hence, should be strictly taken according to prescription. Its side effects include stomach bleeding, peptic ulcer, heartburn, loosening of the skin, etc. Clopidogrel cold lead to peptic ulcer.

7 Foods that Cause Peptic Ulcer

There are foods that should be abstained from as they have high chance of causing Peptic Ulcer. These foods include;

  • Milk
  • Spicy foods
  • Chocolate
  • Coffee
  • Fatty foods
  • Alcohol
  • Foods rich in Citrus, etc.


What can stop ulcer pain immediately?

If you’ve ever had ulcer pain, you’ll know how dreadful and painful it could go every second. For you to acutely stop ulcer pain, take;

  • Plantain bananas
  • Yogurt
  • Honey
  • Turmeric
  • Ginger
  • Garlic, etc.

What are the warning signs of an Ulcer?

The human body shows off certain signs which indicate danger either mild or severe. Hence, below are signs of Ulcer you should take note of;

  • Nausea
  • Burning stomach pain
  • Belching, Bloating
  • Intolerance to fatty food
  • Heartburn, etc.

Once these signs are partially or fully complete, consult a pharmacist for counsel.

What are the two major classes of anti ulcer drugs?

There are drugs that fight the bacteria causing peptic ulcer and these drugs are classified in about three to four classes but we have two major classes. They are:

  • Proton pump inhibitor
  • Selective histamine type 2

Proton pump inhibitors drugs include; Omeprazole, lansoprazole, esomeprazole, pantoprazole, Rabeprazole, etc. Selective histamine type 2 drugs include; Cimetidine, Famotidine, Nizatidine, etc.

What are the types of peptic ulcers?

There are majorly three types of peptic ulcers. They are:

  • Duodenal ulcers
  • Gastric ulcer
  • Oesophageal ulcer.

For a patient diagnosed with peptic ulcer, he should be able to be identified in either of these segments with appropriate medications.

For you to live healthy as an ulcerative patient, abstain from drugs and foods that trigger its effect. Appropriate consumption of your drugs as stated by the health care professional. Keep living healthy!



Please enter your comment!
Please enter your name here